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Research Scientist

Job Created on 23 Sep 2026 California Institute of Technology

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community. Job Summary The Mayo Lab at the California Institute of Technology (Caltech) seeks a motivated Research Scientist with a PhD and postdoctoral training in immunology to advance the lab's research programs focused on autoimmune disease, antigen-specific immune tolerance, and translational immunology. This position will conduct research that follows from the recent Olson et al. PNAS publication (doi: 10.1073/pnas.2501046122). Essential Job Duties Organize, plan, and conduct experiments to study and investigate scientific problems and engineering challenges in immunology.  Drive data generation for high-impact publications and grant applications.  Analyze and present data at lab meetings, conferences, and in manuscripts.  Collaborate with other labs, core facilities, academic institutions, and companies.  Mentor graduate students, postdoctoral fellows, and/or research staff as appropriate.  Partner with Principal Investigator in initiating, writing, and/or submitting grant proposals.  Basic Qualifications PhD in Immunology or a closely related discipline. Must have 5 years of relevant experience (including time spent in predoctoral and postdoctoral training). Demonstrated expertise with mammalian cell culture.  Demonstrated competence with techniques such as ELISA, Western blots, and flow cytometry.  Excellent analytical, organizational, and written and verbal communication skills.  Preferred Qualifications Postdoctoral research experience with a strong publication record.  Demonstrated expertise in cellular and molecular immunology.  Demonstrated expertise in murine or other in vivo models of immune function or autoimmunity. Experience with autoimmune disease, immune tolerance, or chronic inflammation.  Familiarity with translational and/or preclinical research concepts.  Interest in therapeutic modalities (e.g., biologics, nanoparticles, gene-based approaches). Required Documents Resume

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