The global rise in antibiotic-resistant bacteria underscores the urgent need for alternative antimicrobial strategies capable of limiting bacterial growth and viability. We previously demonstrated that weak organic acids and transition metals combine synergistically to strongly inhibit bacterial growth. Here, we extend these findings to determine whether this interaction results only in bacteriostatic suppression or can induce irreversible killing. Using standardized quantitative assays, selected acid-metal combinations achieved rapid bactericidal activity, producing >5-log10 reductions in Gram-negative and Gram-positive bacterial load after brief exposure at concentrations substantially lower than those required for many conventional disinfectants.
Livnat-Levanon, N., Haldar, A., Grupper, M., Lewinson, O.
Advertisement
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 5
- Comments 0