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Rebinding drives cellular retention of small-molecule drugs with abundant targets

Journal content Created on 02 Jun 2026 Proceedings of the National Academy of Sciences

Boyan LiTimothy J. MitchisonaDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115bTherapeutics Graduate Program, Harvard Medical School, Boston, MA 02115cLaboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115

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